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Angiotensin-Specific Blood Collection Tubes (RAAS Testing)

XINLE Angiotensin-Specific Blood Collection Tubes are designed for the collection, stabilization, transportation, and pre-analytical processing of blood specimens for Angiotensin I (Ang I) and Angiotensin II (Ang II) testing. Featuring a patented enzyme inhibitor formula that eliminates traditional ice-bath requirements, these tubes provide an innovative, standardized solution for clinical hypertension management and Renin-Angiotensin-Aldosterone System (RAAS) research.

Product Overview

Manufactured in ISO 13485-compliant facilities, XINLE Angiotensin-Specific Blood Collection Tubes are NMPA Class II certified medical devices protected by CNIPA invention patent technology.

Designed specifically for clinical hypertension panels and cardiovascular biomarker assessment, each tube is pre-loaded with a proprietary stabilization formulation (EDTA-K₂ combined with specific enzyme inhibitors, such as hydroxyquinoline and dimercaptopropanol). This advanced formula effectively arrests angiotensin degradation and enzymatic conversion at room temperature, ensuring diagnostic test results accurately reflect the patient’s true physiological state.

Patented Technology & Key Advantages

  • Ice-Bath-Free Technology: Eliminates the cumbersome requirement for traditional ice-bath collection and cold-chain transport, significantly streamlining laboratory workflows and improving efficiency.
  • Enzymatic Degradation Blockade: Proprietary enzyme inhibitors completely halt the conversion cascade (angiotensinogen → Angiotensin I → Angiotensin II), preventing in vitro biomarker degradation during handling.
  • Factory-Standardized Pre-loading: Pre-filled reagents eliminate concentration errors, contamination risks, and dosing inconsistencies associated with manual on-site reagent preparation.
  • Patent & Regulatory Backing: Protected by a China National Intellectual Property Administration (CNIPA) invention patent and certified as an NMPA Class II medical device.
  • Comprehensive Specification Range: Available in PET and Glass from 1 mL to 10 mL to accommodate diverse clinical and research blood volume requirements.

Clinical & Research Applications

These tubes are primarily used for Renin-Angiotensin-Aldosterone System (RAAS) measurement and clinical hypertension panels (3 or 4 tests):

  • Hypertension Panel (Renin, Angiotensin II, Aldosterone): Classification, differential diagnosis, and treatment monitoring of primary versus secondary hypertension.
  • Plasma Renin Activity (PRA) Assays: Evaluating renin activity levels through the precise measurement of generated Angiotensin I.
  • Angiotensin I & II Testing: Etiology screening for hypertension and related cardiovascular disease research.
  • Secondary Hypertension Screening: Auxiliary diagnostic evaluation of primary aldosteronism and renovascular hypertension.

Note: Fully compatible with standard disposable venous blood collection needles and commercial Angiotensin assay kits.

Product Specifications & Packaging

PRODUCT/MATERIALVolumeAdditiveShelf LifePACKAGING (INNER BOX / CARTON)
Angiotensin-Specific Blood Collection Tube(PET)1ml, 2ml, 3ml, 4ml, 5ml, 6ml, 7ml, 8ml, 9ml, 10mlPatented Stabilizer12months100pcs/1800pcs
Angiotensin-Specific Blood Collection Tube(GLASS)1ml, 2ml, 3ml, 4ml, 5ml, 6ml, 7ml, 8ml, 9ml, 10mlPatented Stabilizer24months100pcs/1800pcs

Operation & Specimen Handling Guide

Follow these standardized steps during specimen collection:

  1. Collection: Perform routine venipuncture using a standard venous blood collection needle.
  2. Blood Volume: Draw the recommended volume (3–4 mL of blood is standard) to maintain the exact pre-loaded additive-to-blood ratio.
  3. Immediate Inversion: Gently invert the tube several times immediately after blood collection to ensure thorough mixing with the anticoagulant and enzyme inhibitors.
  4. Transport & Storage: Transport at room temperature directly to the laboratory (no ice bath required).

Frequently Asked Questions (FAQ)

A: Generally, 3–4 mL of blood is recommended. Drawing an insufficient blood volume may alter the additive-to-blood ratio and adversely affect testing accuracy.

A: Gently invert the tube several times immediately after collection to ensure thorough mixing of the whole blood with the pre-loaded EDTA-K₂ anticoagulant and specific enzyme inhibitors.

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