Blood RNA Preservation Tubes

Product Overview

Manufactured in ISO 13485-compliant facilities, the XINLE Blood RNA Preservation Tube provides a standardized, closed-system pre-analytical solution for molecular diagnostics, transcriptomic profiling, and translational medicine research.

Intracellular RNA is notoriously labile and undergoes rapid degradation and artifactual transcription changes within minutes of blood draw due to endogenous RNases and cellular stress. Our proprietary RNA stabilization chemistry instantly penetrates blood cells to inactivate nucleases and lock the in vivo gene expression profile immediately upon collection, eliminating the urgent need for immediate on-site centrifugation or liquid nitrogen freezing.

Regulatory Notice: For Molecular Diagnostic Research & Clinical Laboratory Use.

Key Features & Biological Advantages

• Immediate Intracellular RNA Stabilization: Rapidly inactivates cellular RNases and prevents ex vivo gene induction or down-regulation, preserving accurate biological information.
• 3-Day Room Temperature Stability: Maintains intact total RNA stability in whole blood for up to 3 days at 20–25°C, drastically reducing dependency on cold-chain logistics and expanding sample collection windows.
• High-Quality & High-Yield RNA Recovery: Optimized stabilization chemistry ensures high RNA Integrity Numbers (RIN) and high-yield extraction compatible with sensitive downstream molecular testing.
• Closed-Tube Contamination Control: Direct-draw evacuated tube design minimizes specimen handling steps, protecting laboratory personnel and preventing exogenous RNase contamination.
• Standardized Sample Workflow: Integrates blood collection, chemical stabilization, ambient storage, and transport into a single traceable workflow for reproducible multi-center clinical trials.
• Broad Downstream Molecular Compatibility: Preserved samples are fully compatible with standard silica-column and magnetic-bead total RNA extraction kits across major automated platforms.

Clinical & Research Applications

XINLE Blood RNA Preservation Tubes are widely utilized in genomic laboratories, biobanks, and clinical oncology centers requiring pristine RNA quality:

• Gene Expression Profiling & Transcriptomics: Accurate quantification of cellular mRNA transcripts and biological pathway modulation.
• RT-PCR & Quantitative qPCR Assays: Reliable amplification and diagnostic validation for infectious diseases and genetic disorders.
• High-Throughput RNA Sequencing (RNA-Seq): Preserving full-length transcriptome integrity for next-generation sequencing and bioinformatics analysis.
• Liquid Biopsy & cfRNA Research: Stabilization and profiling of circulating cell-free RNA biomarkers for non-invasive early disease detection.
• Oncology & Immunological Biomarker Discovery: Investigating transcriptomic signatures associated with cancer progression, autoimmune diseases, and therapeutic responses.
• Molecular Diagnostic Development: Standardized pre-analytical specimen collection for proprietary RNA-based in vitro diagnostic (IVD) test kits.

Product Specifications & Packaging

How to Use Blood RNA Preservation Tubes

Follow these standardized handling procedures to ensure complete RNA protection:

1. Blood Draw: Perform routine venipuncture using a standard venous blood collection needle.
2. Ensure Full Draw: Collect blood until flow ceases to ensure the full 2.5 mL draw volume is reached, maintaining the precise blood-to-stabilizer ratio.
3. Immediate Inversion Mixing: Gently invert the tube 8 to 10 times immediately after blood draw to ensure thorough mixing of whole blood with the pre-loaded RNA stabilization reagent. (Do not shake vigorously to avoid mechanical cell shearing).
4. Ambient Transport: Store and ship samples at room temperature (20–25°C) directly to the processing laboratory within 3 days.

Frequently Asked Questions (FAQ)